Nomogram to predict overall survival of patients with pseudomyxoma peritonei of appendiceal origin: A retrospective cohort study

Background Pseudomyxoma peritonei (PMP) is a rare disease, with the rate of overall survival (OS) influenced by many factors. The present study aimed to define independent predictors and establish nomogram for individual risk prediction in PMP patients. Methods One hundred forty-seven patients were consecutively included between June 1, 2013, November 22, 2019. log-rank test was used compare OS groups; subsequently, variables p < .10 subjected multivariate Cox modeling defining indicators. Finally, established based on prognosticators assessed internal validation. Results Multivariate analysis showed that D-dimer level, carbohydrate antigen (CA) 125 CA 19-9 degree radical surgery, histological grade all independently associated A plotted underwent discrimination ability revealed good predictive as indicated C-index value (0.825), calibration plots confirmed consistency predicted observed probabilities. Conclusions Five prognostic factors predicting identified, these indicators reasonable prediction.